Lec 27 | MIT 7.012 Introduction to Biology, Fall 2004
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Nervous System 2 (Prof. Eric Lander) The MIT Biology Department core courses, 7.012, 7.013, and 7.014, all cover the same core material, which includes the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. 7.012 focuses on the exploration of current research in cell biology, immunology, neurobiology, genomics, and molecular medicine. A Member of Whitehead Institute and Founding Director of the Broad Institute of MIT and Harvard, Eric S. Lander is one of the driving forces behind today’s revolution in genomics, the study of all of the genes in an organism and how they function together in health and disease. ERIC LANDER: Lander was a world leader of the international Human Genome Project, the effort to map the blueprint for a human being. Under his leadership, the Whitehead/MIT Center for Genome Research (which formed the core of the Broad Institute) was responsible for developing many of the key tools of modern mammalian genomics and was the leading contributor to the Human Genome Project. Today, Lander is using the knowledge of the human genome to tackle the fundamental issue of medicine: to find the causes versus the symptoms of disease. He believes this will take comprehensive attacks. It entails understanding all of the genes and the gene products and how they work in the cell, looking at the circuits in which they work, and understanding the genetic variation in the population. Doing so requires cooperation across scientific disciplines from basic biology to chemistry, and from basic science to clinical science, as well as collaboration across i
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