The reasons the rheumatoid arthritis disease remain unknown. Several studies are being conducted in order to know the reason of this disease. The chance to get the disease can be hereditary too. For the people who are more likely to get rheumatoid arthritis, can get it from some infections or several other factors in the environment. Such people will have the immune system which is likely to cause damage up on the own body tissues. This can also promote the damage to other body parts like lungs, eyes, etc. The factors like smoking and the pollution in the environment can all develop and worsen rheumatoid arthritis. Usually the symptoms or signs of this disease may come and go according to the intensity of the tissue inflammation. When the disease is active or over active, inflammations in the tissues will be there. The lessening of the disease may also last for either weeks and months or years. During that period, the patient will also feel that he is in good health. But when there is a return of the disease, the symptoms also comes back and this is known as flare. Other symptoms include loss of energy, loss of appetite, fatigue, muscle pain, joint pain, low fever etc. The stiffness in the joints and muscles will be most prominent in the morning and after the period of the reduction. Some times, there may be the inflammation only in one of the joints. Even the simple daily chores may seem much difficult for the patients to do.